WHAT IS PHOTODYNAMIC THERAPY?
Photobiomodulation or Photo dynamic therapy (PDT) formerly called low level laser therapy (LLLT) is a treatment that uses a drug, called a photosensitizer or photosensitizing agent, and a particular type of light. When photosensitizers are exposed to a specific wavelength of light, they produce a form of oxygen that kills nearby cells.
Each photosensitizer is activated by light of a specific wavelength. This wavelength determines how far the light can travel into the body. Until recently laser light could only penetrate 1 to 2 cm into the body, but with the new technology, penetration can go very deep into the body and by combining specific photosensitizers and wavelengths of light we are able to treat many different areas of the body with PDT.
Each photosensitizer is activated by light of a specific wavelength. This wavelength determines how far the light can travel into the body. Until recently laser light could only penetrate 1 to 2 cm into the body, but with the new technology, penetration can go very deep into the body and by combining specific photosensitizers and wavelengths of light we are able to treat many different areas of the body with PDT.
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For over forty years, low level laser (light) therapy (LLLT) and LED (light emitting diode) therapy (also known as photobiomodulation) has been shown to reduce inflammation and edema, induce analgesia, and promote healing in a range of musculoskeletal pathologies.
The current and widely accepted proposal is that low level visible red to near infrared light (NIR) energy is absorbed by mitochondria and converted into ATP for cellular use. In addition, the process creates mild oxidants (ROS), which leads to gene transcription and then to cellular repair and healing. The process also unclogs the chain that has been clogged by nitric oxide. |
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The nitric oxide is then released back into the system. Nitric oxide is a molecule that our body produces to help its trillions of cells communicate with each other. This communication happens by transmission of signals throughout the entire body. Additionally, nitric oxide helps to dilate the blood vessels and improve blood circulation.
Dr. M. Weber has developed a modern system for using this technology in various ailments. For treatment possibilities please follow the below link. |
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HOW IS PDT USED TO TREAT CANCER?
Photodynamic therapy (PDT) is a two-stage treatment that combines light energy with a drug (photosensitizer) designed to destroy cancerous and precancerous cells after light activation. Photosensitizers are activated by a specific wavelength of light energy, usually from a laser. The photosensitizer is nontoxic until it is activated by light. However, after light activation, the photosensitizer becomes toxic to the targeted tissue.
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In the first step of PDT for cancer treatment, a photosensitizing agent is injected into the bloodstream. The agent is absorbed by cells all over the body but stays in cancer cells longer than it does in normal cells.
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Approximately 24 to 72 hours after injection, when most of the agent has left normal cells but remains in cancer cells, the tumor is exposed to light. The photosensitizer in the tumor absorbs the light and produces an active form of oxygen that destroys nearby cancer cells.
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In addition to directly eliminating cancer cells, PDT appears to shrink or destroy tumors in two other ways. The photosensitizer can damage blood vessels in the tumor, thereby preventing cancer from receiving necessary nutrients. PDT also may activate the immune system to attack the tumor cells.
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The light used for PDT in our partner clinic at Meber Med come from a laser as explained in the video beside. Laser light can be directed through fiber optic cables, thin fibers that transmit light, to deliver light to areas inside the body. In our treatment, we are using a Nanoparticle technology where the photosensitizer is embedded in liposomes allowing a treatment with infrared light penetrating deep into the body. PDT is usually performed as an outpatient procedure and can be repeatedly performed alone or may be used with other therapies, such as surgery, radiation therapy or chemotherapy. |
Extracorporeal photopheresis (ECP) is a type of PDT in which a machine is used to collect the patient’s blood cells, treat them outside the body with a photosensitizing agent, expose them to light, and then return them to the patient. The U.S. Food and Drug Administration (FDA) has approved ECP to help lessen the severity of skin symptoms of cutaneous T-cell lymphoma that has not responded to other therapies. Studies are underway to determine if ECP may have some application for other blood cancers, and also to help reduce rejection after transplants.
PHOTOSENSITIZER COMBINATION
WITH MEDICAL LASER THERAPY
A curcumin therapy can be combined with medical laser therapy very successfully because curcumin acts as a photosensitizer and absorbs light in the blue range.
The active ingredient curcumin is derived from the rhizome of the medicinal plant Curcuma (Curcuma longa; turmeric), which belongs to the ginger family. In India and Southeast Asia, Curcuma has been used in Ayurveda, one of the world’s oldest medical systems, since thousands of years. And for good reason: Curcuma has an extremely diverse potential and can support the treatment of numerous medical conditions. It also contains phytonutrients (polyphenols) which have various health effects.
The active ingredient curcumin is derived from the rhizome of the medicinal plant Curcuma (Curcuma longa; turmeric), which belongs to the ginger family. In India and Southeast Asia, Curcuma has been used in Ayurveda, one of the world’s oldest medical systems, since thousands of years. And for good reason: Curcuma has an extremely diverse potential and can support the treatment of numerous medical conditions. It also contains phytonutrients (polyphenols) which have various health effects.
ULTRAPURE + PRO
The previous version UltraCur+ already had an extremely high bioavailability due to a special protein binding. But we did not want to be satisfied with that. Instead of a whey protein, the new version contains N-acetylcysteine (NAC, ACC), a synthetically produced chemical compound and derivative of the naturally occurring amino acid cysteine. It has anti-inflammatory and detoxifying properties and is considered an antioxidant.
NAC is quickly absorbed by the body. One capsule of the pro version (600 mg) contains 60 mg of pure curcumin and corresponds to 4 capsules of the former product UltraCur+.
The reason why we changed the formula is that N-acetylcysteine can bind 4x more curcumin than the whey protein. For a patient, this means a lower intake amount and an even better bioavailability. Our experimental data shows that UltraCur+Pro can achieve a more than four times higher curcumin concentration in the plasma which means that the absorption could also be improved.
Suggested dose:
Curcumin’s absorption maximum is at about 440 nm. It even acts phototoxic in low concentrations (for example to bacteria), and also proapoptotic, anti-inflammatory, immune-stimulating, radioprotective, chemoprotective, antitumoral, antimetastatic, anti-angiogenic, radiosensitizing and chemosensitizing.
Thus, curcumin is a potent photosensitizer for PDT in the treatment of psoriasis, tumors, infections and other diseases.
In addition, the blue laser improves micro circulation by NO release and has strong anti-inflammatory and antibacterial effects, which in turn accelerate the healing process and contribute to pain relief.
We are providing with our partner clinic in Germany Photodynamic Cancer Therapy. For further details please provide us with your latest medical record and ask for treatment information by clicking on the button below.
NAC is quickly absorbed by the body. One capsule of the pro version (600 mg) contains 60 mg of pure curcumin and corresponds to 4 capsules of the former product UltraCur+.
The reason why we changed the formula is that N-acetylcysteine can bind 4x more curcumin than the whey protein. For a patient, this means a lower intake amount and an even better bioavailability. Our experimental data shows that UltraCur+Pro can achieve a more than four times higher curcumin concentration in the plasma which means that the absorption could also be improved.
Suggested dose:
- Preventive: 1 Capsule/day | now in the upcoming cold and flu season!
- Accompanying Therapy: 2 Capsules/day
- In Combination with Laser-Therapy (PDT): 4 Capsules/day
Curcumin’s absorption maximum is at about 440 nm. It even acts phototoxic in low concentrations (for example to bacteria), and also proapoptotic, anti-inflammatory, immune-stimulating, radioprotective, chemoprotective, antitumoral, antimetastatic, anti-angiogenic, radiosensitizing and chemosensitizing.
Thus, curcumin is a potent photosensitizer for PDT in the treatment of psoriasis, tumors, infections and other diseases.
In addition, the blue laser improves micro circulation by NO release and has strong anti-inflammatory and antibacterial effects, which in turn accelerate the healing process and contribute to pain relief.
We are providing with our partner clinic in Germany Photodynamic Cancer Therapy. For further details please provide us with your latest medical record and ask for treatment information by clicking on the button below.
Sources:
The National Cancer Institute, WeberMed
Disclaimer:
Please note, for regulatory reasons, there is a disclaimer on all our Social Media Pages including but not limited to our Facebook´s and Aristoloft Website, showing that all data is for educational purposes only. Products mentioned, and information provided, are not intended to diagnose, treat, cure, or prevent any disease and as with any personal and anecdotal testimony, application results may vary also in countries where alternative cellular treatments are permitted.
The National Cancer Institute, WeberMed
Disclaimer:
Please note, for regulatory reasons, there is a disclaimer on all our Social Media Pages including but not limited to our Facebook´s and Aristoloft Website, showing that all data is for educational purposes only. Products mentioned, and information provided, are not intended to diagnose, treat, cure, or prevent any disease and as with any personal and anecdotal testimony, application results may vary also in countries where alternative cellular treatments are permitted.
